From CBS Sports · · 1m
NFL Week 3 Betting Picks 2026
SportsLine experts predict NFL Week 3 totals and spreads for Sunday's games
In brief
SportsLine experts predict NFL Week 3 totals and spreads for Sunday's games Chargers vs. Bills game likely to exceed 50.5 points Originally reported by CBS Sports.
Bills vs Chargers
SportsLine predicts over 50.5 points in Bills-Chargers game
“So far, new chargers offensive coordinator mike mcdaniel isn't flexing much”
Browns vs Panthers
Browns favored by 2.5 points in Panthers-Browns matchup
“Bryce young has carved up two bad defenses but both were zone-heavy schemes”
Colts vs Texans
Colts favored by 1.5 points in Colts-Texans game
“Houston's offensive line is struggling with c.j. stroud facing more pressure”
Patriots vs Jaguars
Patriots favored by 3 points in Patriots-Jaguars game
“The patriots enjoyed a comfortable win against a steelers team that couldn't move the ball”
Giants vs Titans
Titans favored by 2.5 points in Giants-Titans game
“The titans averaged a healthy five point seven yards per play in their loss to philadelphia”
Seahawks vs Commanders
Seahawks favored by 7.5 points in Seahawks-Commanders game
“Drew lock has delivered strong numbers thus far with the washington defense having no answer for cee dee lamb”
Cardinals vs 49ers
Cardinals favored by 8.5 points in Cardinals-49ers game
“The forty nines started the season with a pair of blowouts while the cardinals crashed back to earth”
Vikings vs Buccaneers
Justin Jefferson over 68.5 receiving yards in Vikings-Buccaneers game
“Coming off a rain-soaked game in which the vikings hardly had the ball”
Rams vs Broncos
Rams favored by 2.5 points in Rams-Broncos game
“Aaron donald made his season debut and played thirty two snaps”
Eagles vs Bears
Eagles under 44.5 points in Eagles-Bears game
“The eagles have shown me nothing through two weeks on offense with three hundred and eighteen and three hundred and forty one yards”
The short version
Chargers vs. Bills game likely to exceed 50.5 points



