Week 4 NFL Betting Lines

Week 4 NFL odds and spreads for key matchups.

Oct 4, 2026

5 cards · 50s · tap to begin

From · · 50s

Week 4 NFL Betting Lines

Week 4 NFL odds and spreads for key matchups.

In brief

Week 4 NFL odds and spreads for key matchups. Texans lead Cowboys by 2.5 points in Week 4 NFL betting lines. Originally reported by CBS Sports.

Week 4 NFL Betting Lines

Sunday's NFL schedule features pivotal matchups including Cowboys vs. Texans, Patriots vs. Bills, Chiefs vs. Raiders and Lions vs. Panthers.

Texans -2.5 Point Favorite

Texans are 2.5-point favorites at home against the Cowboys despite Houston being winless through the first three weeks.

Key Week 4 Spreads

Key Week 4 Spreads

Patriots vs. Bills spread is Bills -6.5, Jaguars vs. Bengals is Bengals -2.5, and Raiders vs. Chiefs is Chiefs -4.5.

Highest Total Points

Lions vs. Panthers total is 51.5 points on Sunday Night Football.

Betting Promotions

New users get $150 in bonus bets after a $5 wager with DraftKings, and other sites offer sign-up bonuses.

The bottom line

Texans lead Cowboys by 2.5 points in Week 4 NFL betting lines.

Read the original on CBS Sports

React

Sign in to react and comment.

Comments (0)

Life is short. Keep it sweet. Respect others' opinions and be kind!

    Recommended next

    More decks on nfl and related topics.