Oxaloacetate supplement claims

Users report lifting fatigue and brain fog within days of taking oxaloacetate.

“I feel like a brand-new person”

Oxaloacetate's role in body

Oxaloacetate is a compound produced naturally by the body that helps cells generate energy.

UCLA study on breast cancer survivors

16 women taking oxaloacetate for eight weeks reported improved memory and concentration.

Cognitive improvements

Scores on cognitive difficulty measures moved from impaired to normal range after eight weeks.

Study limitations

The study was small and lacked a placebo group, so researchers cannot confirm oxaloacetate caused improvements.

Digestive side effects

Two women stopped taking oxaloacetate due to nausea and bloating.

Long Covid study

A separate study found oxaloacetate helped some long Covid patients with cognitive issues.

ME/CFS benefits

Some ME/CFS patients reported reduced fatigue and improved cognitive function with oxaloacetate.

Cost of supplement

At 1,000mg daily dose, oxaloacetate costs over $500 per month for a standard product.

Long-term effects unknown

It's unclear if benefits last after stopping oxaloacetate or if longer courses are needed.

Next steps

Researchers plan a larger placebo-controlled trial to confirm oxaloacetate's effects.

Why it might work

Oxaloacetate could help restore normal cellular energy production or reduce neuroinflammation.

Current recommendations

Experts caution oxaloacetate is not yet proven for brain fog and recommend more research.

Oxaloacetate's potential

Early research suggests oxaloacetate could be a promising treatment for cognitive issues after cancer treatment.