Christina Applegate's MS Misdiagnosis Mystery

Christina Applegate's MS misdiagnosis leaves her 'back at square one' as doctors confirm misdiagnoses are 'fairly common'.

Oct 20, 2026

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Christina Applegate's MS Misdiagnosis Mystery

Christina Applegate's MS misdiagnosis leaves her 'back at square one' as doctors confirm misdiagnoses are 'fairly common'.

In brief

Christina Applegate's MS misdiagnosis leaves her 'back at square one' as doctors confirm misdiagnoses are 'fairly common'. Christina Applegate's multiple sclerosis misdiagnosis is now a mystery after new technology revealed she doesn't have the condition. Originally reported by LADbible.

Christina Applegate's MS Diagnosis

Her illness is now a mystery (Leon Bennett/Getty Images)

Christina Applegate was diagnosed with multiple sclerosis in 2021 but now faces uncertainty about her condition.

Misdiagnosis Prevalence

Christina Applegate is 'not happy at all' about the news of her misdiagnosis (Axelle/Bauer-Griffin/FilmMagic)

Nearly 20 percent of people diagnosed with MS later find they don't have the condition, according to Dr Marwa Kaisey.

Doctor's Explanation

Applegate says she's 'back at square one' (Instagram/@christinaapplegate)

Dr Marwa Kaisey explained there's no single test for MS and misdiagnosis remains a problem with significant clinical implications.

Applegate's Reaction

(LADbible)

Applegate says she's 'back at square one' as her symptoms persist and her illness is now a mystery.

“back at square one”

Misdiagnosis Causes

Conditions mistaken for MS include migraine, cerebral small vessel disease, fibromyalgia, and neuromyelitis optica spectrum disorders.

What matters most

Christina Applegate's multiple sclerosis misdiagnosis is now a mystery after new technology revealed she doesn't have the condition.

Read the original on LADbible

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