Christina Applegate's MS Misdiagnosis Reveal

Christina Applegate says she doesn't have MS after years of symptoms and misdiagnosis.

Oct 20, 2026

8 cards · 1m 20s · tap to begin

From · · 1m 20s

Christina Applegate's MS Misdiagnosis Reveal

Christina Applegate says she doesn't have MS after years of symptoms and misdiagnosis.

In brief

Christina Applegate says she doesn't have MS after years of symptoms and misdiagnosis. Christina Applegate's doctors confirmed she doesn't have multiple sclerosis after years of symptoms and misdiagnosis. Originally reported by New York Post.

Applegate's MS Diagnosis Reversal

Christina Applegate speaks at a podium alongside a presenter at the Emmy Awards.

Christina Applegate says she's back at square one after five years believing she had multiple sclerosis.

“Congratulations. You don't have MS”

Symptoms of Worsening Health

Christina Applegate speaks into a microphone onstage, holding a glittery cane, while standing beside another woman at a concert.

Applegate reported tingling in her toes that led to 'insane tingling' from her butt down and leg buckling during filming.

“My knees feel like I have bricks attached to them, heavy and painful”

MS Misdiagnosis Statistics

MS Misdiagnosis Statistics

Up to 1 in 5 patients diagnosed with MS may not actually have MS but a different condition.

“Symptoms of MS are not unique to MS”

MS Symptoms and Progression

MS affects nearly 1 million Americans and can cause vision problems, muscle weakness, and cognitive changes.

“Muscle weakness and pain can affect walking or standing or lead to paralysis”

Applegate's Current Health Status

Applegate requires a wheelchair during filming and walks with a cane since 2021, with severe knee pain and numbness.

“When I put my feet down on the ground when I wake up, it feels as if the floor is made of needles”

Next Steps for Diagnosis

Christina Applegate attends the 25th Annual Critics' Choice Awards.

Applegate's doctors are embarking on an online investigation to find the cause of her health issues since 2021.

“It's important to talk to a neuroimmunologist at an academic center to review whether this is autoimmune”

Possible Causes of Symptoms

Rheumatoid arthritis and other autoimmune conditions are being explored as potential causes of Applegate's symptoms.

“There's probably something causing inflammation within her central nervous system”

MS Mimics and Misdiagnosis

Conditions like rheumatoid arthritis, Lyme disease, and syphilis can mimic MS symptoms and lead to misdiagnosis.

“Tingling or blurry vision can occur due to dozens of other diagnoses”

Here's the gist

Christina Applegate's doctors confirmed she doesn't have multiple sclerosis after years of symptoms and misdiagnosis.

Read the original on New York Post

React

Sign in to react and comment.

Comments (0)

Life is short. Keep it sweet. Respect others' opinions and be kind!

    Recommended next

    More decks on christina applegate and related topics.