NFL Week 6 Betting Shifts

49ers surge as Super Bowl favorite after Rams collapse.

Oct 20, 2026

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NFL Week 6 Betting Shifts

49ers surge as Super Bowl favorite after Rams collapse.

In brief

49ers surge as Super Bowl favorite after Rams collapse. The 49ers overtook the Rams as Super Bowl favorites after a 6-0 start, while Eagles odds plummeted due to Jalen Hurts' injury. Originally reported by New York Post.

49ers become Super Bowl favorites

49ers become Super Bowl favorites

The 49ers improved to 6-0 with a win over Washington, moving from +680 to +540 at DraftKings Sportsbook.

Rams fall from Super Bowl favorite

The Rams dropped to 2-4 after a loss to the Cardinals, plummeting from +700 to 12/1 in one week.

Eagles odds collapse

Philadelphia Eagles quarterback Jalen Hurts (1) drops back to pass.

Philadelphia’s Super Bowl odds fell from 40/1 to 200/1 after Jalen Hurts missed the rest of the season due to blood clots.

Chiefs underdogs against Seahawks

Kansas City Chiefs quarterback Patrick Mahomes scrambles with the football during a game against the Indianapolis Colts.

Kansas City remains undefeated but is now a 2.5-point underdog against the Seahawks, their first time as underdogs.

The big picture

The 49ers overtook the Rams as Super Bowl favorites after a 6-0 start, while Eagles odds plummeted due to Jalen Hurts' injury.

Read the original on New York Post

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