Estuary Biotherapeutics Launches With $103 Million

Estuary Biotherapeutics secures $103 million to develop gene therapies for kidney disease.

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Oct 17, 2026

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Estuary Biotherapeutics Launches With $103 Million

Estuary Biotherapeutics secures $103 million to develop gene therapies for kidney disease.

In brief

Estuary Biotherapeutics secures $103 million to develop gene therapies for kidney disease. Estuary Biotherapeutics received $103 million to create gene therapies targeting kidney disease. Originally reported by Pulse 2.0.

Estuary Biotherapeutics Launches

Estuary Biotherapeutics has launched with $103 million in committed financing to develop genetic medicines targeting serious kidney diseases.

Funding Sources

The financing includes a $93 million Series A led by RA Capital Management with participation from Deep Track Capital, Biogen New Ventures, UPMC Enterprises, Pivotal bioVenture Partners, the National Kidney Foundation Innovation Fund and a…

Lead Programs

The proceeds will support Estuary’s two lead programs, EST-201 and EST-101, through clinical proof of concept and further development of the company’s kidney-targeting platform.

Program Targets

EST-201 targets patients with ADPKD caused by PKD2 mutations, while EST-101 targets patients with PKD1 mutations.

Clinical Timeline

Estuary anticipates bringing EST-201 into the clinic in 2027 and EST-101 into the clinic in 2028.

The takeaway

Estuary Biotherapeutics received $103 million to create gene therapies targeting kidney disease.

Read the original on Pulse 2.0

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