# Actress Christina Applegate says she was misdiagnosed with MS

> Actress Christina Applegate reveals she was misdiagnosed with MS, a condition affecting nearly 1 million Americans.
- Title: Actress Christina Applegate says she was misdiagnosed with MS
- Summary: Actress Christina Applegate reveals she was misdiagnosed with MS, a condition affecting nearly 1 million Americans. Actress Christina Applegate says she was…
- Keywords: christina applegate, multiple sclerosis, podcast, health, ms diagnosis, misdiagnosis, news, politics, world, Actress, Christina, Applegate
- Source: Straight Arrow — https://san.com/cc/actress-christina-applegate-says-she-was-misdiagnosed-with-ms-and-thats-pretty-common
- Published: 2026-10-20T17:40:04+00:00
- Read time: 1 min
- Topics: christina applegate, multiple sclerosis, podcast, health, ms diagnosis, misdiagnosis, news, politics, world
## Christina Applegate's MS diagnosis
Actress Christina Applegate says she was misdiagnosed with multiple sclerosis, a condition affecting nearly one million Americans.

> Congratulations, you don’t have MS
## Misdiagnosis common in MS cases
A neurologist states nearly 20% of people diagnosed with MS do not actually have the disease.

> Almost 1 in 5 of these people who’d been told they had MS, some for decades, didn’t actually have it
## MS diagnosis process
MS is diagnosed using a list of criteria rather than a single definitive test, according to a Cedars-Sinai neurologist.

> We don’t have one single test for MS
## Applegate's symptoms persist
Applegate says her symptoms worsened after learning she was misdiagnosed, including fatigue and mobility issues.

> I haven’t gotten better, Jamie! If anything, I’ve gotten worse
## Impact on life
Applegate lost her job and has ongoing mobility challenges despite the corrected diagnosis.

> I lost my job. I lost, I’m sorry. What do you say to someone who’s been living with this for six years
## MS affects central nervous system
Multiple sclerosis disrupts information flow in the brain and between the brain and the rest of the body.

> Multiple Sclerosis is a disease of the central nervous system, which includes the brain, spinal cord and optic nerves
## MS treatment challenges
There is no known cure for MS, but medications reduce inflammation and slow disease progression.

> Treatment usually consists of medications to reduce inflammation and slow the progression of the disease
## Misdiagnosis consequences
Many misdiagnosed patients were on medication for MS they do not actually have, causing financial and health risks.

> A majority of them were on medication to treat their MS
## Key takeaway

Actress Christina Applegate says she was misdiagnosed with MS, a condition that affects nearly 1 million Americans.