# AlphaGenome Atlas: DeepMind's Map of 9 Billion Genetic Mutations

> Google DeepMind's 1-petabyte database maps the impact of every possible single-letter DNA mutation, accelerating rare disease and genomic research.
- Title: AlphaGenome Atlas: DeepMind's Map of 9 Billion Genetic…
- Summary: Google DeepMind's 1-petabyte database maps the impact of every possible single-letter DNA mutation, accelerating rare disease and genomic research…
- Keywords: genomics, deepmind, dna, biotech, technology, startups, AlphaGenome, Atlas, DeepMind's, Map, Billion, Genetic
- Source: Google — https://blog.google/innovation-and-ai/models-and-research/google-deepmind/alphagenome-atlas
- Published: 2026-09-08T00:00:00+00:00
- Read time: 1 min
- Topics: genomics, ai, deepmind, dna, biotech, technology, startups
## Mapping the genome's hidden dark matter
While scientists understand the 2% of the human genome that codes for proteins, the remaining 98% of non-coding DNA has long been a mystery.

> Scientists understand the 2% of the human genome that codes for proteins relatively well, but have only limited knowledge of the remaining 98%.
## A 1-petabyte database of mutations
AlphaGenome Atlas pre-calculates the biological impact of all 9 billion possible single-letter DNA changes across the entire human genome.

> a database that predicts the effects of every possible single nucleotide variant in the human genome.
## One score to prioritize research
The AlphaGenome Variant Impact (AVI) score combines predictions for coding and non-coding DNA, allowing scientists to rapidly pinpoint actionable mutations.

> This single, easy-to-use score combines predictions for both coding and non-coding regions
## Unlocking cold cases in rare diseases
Researchers at the Broad Institute used the AVI score to identify a hidden splice site mutation in the DNM1 gene, solving an unexplained rare disease case.
## Revealing 22% more genetic links
Analyzing UK Biobank data with the Atlas helped scientists identify 19 genome regions tied to BMI and boost non-coding variant discoveries by 22%.
## Democratizing access for all researchers
A zero-code web portal makes the 1-petabyte Atlas accessible to clinicians and biologists worldwide without needing computational expertise.
## Key takeaway

AlphaGenome Atlas maps all 9 billion single-letter DNA variants into an easy-to-query dataset, enabling researchers to instantly pinpoint disease-causing mutations.