# AMD MI325X GPUs Hit 97 TCUPS in Protein Search

> AMD's MI325X GPUs process 97 trillion cell updates per second in protein search tests, outperforming Nvidia's H100.
- Title: AMD MI325X GPUs Hit 97 TCUPS in Protein Search · TokenPost
- Summary: AMD's MI325X GPUs process 97 trillion cell updates per second in protein search tests, outperforming Nvidia's H100. AMD's MI325X GPUs reached 97 TCUPS in…
- Keywords: amd, mi325x, protein search, nvidia, h100, gpu, benchmark, uniref50, mmseqs2, rocm, protein folding, gene annotation
- Source: TokenPost — https://tokenpost.com/news/technology/32099
- Published: 2026-10-14T21:52:31+00:00
- Read time: 1 min
- Topics: amd, mi325x, protein search, nvidia, h100, gpu, benchmark, uniref50, mmseqs2, rocm, protein folding, gene annotation
## AMD MI325X GPU Benchmark
AMD's Instinct MI325X GPUs processed up to 97 trillion cell updates per second in a protein search test.
## Outperformed Nvidia H100
The MI325X outperformed Nvidia's H100 in every tested configuration, while AMD's MI300X performed comparably or faster.
## Protein Search Applications
Evolutionary searches help provide biological data for protein-fold prediction, gene annotation and protein design.
## Key takeaway

AMD's MI325X GPUs reached 97 TCUPS in protein search benchmarks, surpassing Nvidia's H100 in speed for biological sequence analysis.