# Better Biotech ETF: FBT vs PBE Comparison

> First Trust's FBT outperforms Invesco's PBE with lower fees and larger assets.
- Title: Better Biotech ETF: FBT vs PBE Comparison · The Motley Fool
- Summary: First Trust's FBT outperforms Invesco's PBE with lower fees and larger assets. First Trust's FBT has lower expense ratio (0.55%) and higher assets under…
- Keywords: first trust, invesco, fbt, pbe, biotech etf, expense ratio, assets under management, biotech industry, The Motley Fool
- Source: The Motley Fool — https://fool.com/coverage/etfs/2026/11/14/better-biotech-etf-first-trust-s-fbt-vs-invesco-s-pbe
- Author: Robert Izquierdo
- Published: 2026-11-14T20:04:51+00:00
- Read time: 1 min
- Topics: first trust, invesco, fbt, pbe, biotech etf, expense ratio, assets under management, biotech industry, finance, money
## Key Comparison
The First Trust NYSE Arca Biotechnology Index Fund has a lower expense ratio and significantly higher assets under management (AUM).
## Performance History
FBT outperformed PBE on 1-year total return (35.7% vs 28.1%) and five-year returns (1,709 vs 1,382 for $1,000).
## Portfolio Structure
Both ETFs hold 30-31 healthcare stocks with 100% sector weighting, but FBT uses a single index while PBE uses multi-factor analysis.
## Expense Ratio
FBT charges 0.55% versus PBE's 0.59% expense ratio, making it the more affordable option for investors.
## Liquidity Advantage
FBT has higher average trading volume (70,500) compared to PBE's 18,400, indicating better liquidity.
## Dividend Difference
PBE pays a 1.3% dividend yield while FBT has no dividend distribution.
## Key takeaway

First Trust's FBT has lower expense ratio (0.55%) and higher assets under management ($3.0 billion) than Invesco's PBE (0.59%, $438.0 million).