# Christina Applegate tearfully announces she does not have MS and was 'misdiagnosed' for years

> Christina Applegate reveals she was misdiagnosed with MS for years after doctor says she doesn't have the condition.
- Title: Christina Applegate tearfully announces she does not have MS…
- Summary: Christina Applegate reveals she was misdiagnosed with MS for years after doctor says she doesn't have the condition. Christina Applegate says she was…
- Keywords: christina applegate, multiple sclerosis, misdiagnosis, messy podcast, doctor, hospitalization, symptoms, wheelchair, cane, depression, memoir, you with the sad eyes
- Source: Dailymail — https://dailymail.com/tvshowbiz/article-16223501/Christina-Applegate-MS-misdiagnosed-messy-podcast.html?ito=1490&ns_campaign=1490&ns_mchannel=rss
- Published: 2026-10-20T12:10:31+00:00
- Read time: 2 min
- Topics: christina applegate, multiple sclerosis, misdiagnosis, messy podcast, doctor, hospitalization, symptoms, wheelchair, cane, depression, memoir, you with the sad eyes
## Christina Applegate reveals MS misdiagnosis
Christina Applegate tearfully announces she does not have multiple sclerosis despite battling debilitating symptoms for more than five years.

> She came into my room and said, 'Congratulations, you don’t have MS'
## Applegate's MS diagnosis history
Applegate, 54, announced her MS diagnosis in summer 2021 after being hospitalized multiple times since then.
## Applegate's symptoms and struggles
Applegate has relied on a wheelchair and cane for years and been forced to step away from her acting career due to MS symptoms.
## Applegate's emotional impact
Applegate described experiencing a great depression after her MS diagnosis and losing her job and sense of purpose.
## Applegate's hospitalization
Applegate was recently hospitalized and has been in the hospital for months due to her MS symptoms.
## Applegate's podcast revelation
Applegate shared her MS misdiagnosis revelation on a new episode of her Messy podcast with co-host Jamie-Lynn Sigler.
## Applegate's doctor's statement
Applegate's doctor told her she does not have multiple sclerosis despite her symptoms and hospitalizations.

> She came into my room and said, 'Congratulations, you don’t have MS'
## Applegate's current state
Applegate is still in a state of shock and seeking answers about the true nature of her illness.
## Applegate's memoir
Applegate published her memoir 'You With The Sad Eyes' in March 2026 detailing her MS struggles and emotional journey.
## Applegate's hospitalization details
Applegate was hospitalized in Los Angeles since late March 2026 and has been in the hospital for months.
## Applegate's medical history
Applegate has been hospitalized upwards of 30 times since her MS diagnosis in 2021.
## Applegate's emotional state
Applegate described feeling like she had lost everything and was in a state of confusion after her misdiagnosis.
## Applegate's doctor's insight
Doctor Marwa Kaisey explained that MS is often misdiagnosed as there is no single test for the condition.
## Applegate's current challenges
Applegate is still struggling with symptoms and has no clear explanation for her condition.
## Applegate's future plans
Applegate plans to continue her podcast and memoir work while seeking answers about her condition.
## Key takeaway

Christina Applegate says she was misdiagnosed with multiple sclerosis for years after her doctor told her she doesn't have the condition.