# Commanders vs. 49ers MNF Odds

> 49ers favored 7.5 points in Monday Night Football clash.
- Title: Commanders vs. 49ers MNF Odds · CBS Sports | Shortify
- Summary: 49ers favored 7.5 points in Monday Night Football clash. San Francisco 49ers lead Washington Commanders by 7.5 points in Monday Night Football odds.
- Keywords: san francisco 49ers, washington commanders, monday night football, nfl, odds, betting preview, christian mccaffrey, terry mc laurin, george kittle, brock purdy, sports, Commanders
- Source: CBS Sports — https://cbssports.com/betting/news/commanders-49ers-odds-prediction-betting-preview-start-time-monday-night-football-picks-best-bets
- Published: 2026-10-19T23:01:34+00:00
- Read time: 1 min
- Topics: san francisco 49ers, washington commanders, monday night football, nfl, odds, betting preview, christian mccaffrey, terry mc laurin, george kittle, brock purdy, sports
## MNF Odds
San Francisco 49ers host Washington Commanders at 8:15 p.m. et.
## 49ers -7.5
San Francisco 49ers favored 7.5 points with 106 odds.
## Over/Under
51.5 total points expected in game.
## Player Props
Christian McCaffrey -265 to score touchdown, Terry McLaurin -146 for 4+ receptions.
## 49ers Strength
49ers 5-0, Commanders 1-3-1 with 13:2 touchdown-to-interception ratio.
## Commanders Struggles
Commanders tied with Giants after failed field goal attempt.
## Key takeaway

San Francisco 49ers lead Washington Commanders by 7.5 points in Monday Night Football odds.