# Keltie Knight Reveals Prozac's Impact on Sex Drive

> Keltie Knight, 44, explains how Prozac reduced her sex drive despite improving mental health.
- Title: Keltie Knight Reveals Prozac's Impact on Sex Drive | Shortify
- Summary: Keltie Knight, 44, explains how Prozac reduced her sex drive despite improving mental health. Keltie Knight, 44, says Prozac killed her sex drive but helped…
- Keywords: keltie knight, prozac, sex drive, hsdd, addyi, ladygang, perimenopause, ob-gyn, sprout pharmaceuticals, atrum health, Keltie, Knight
- Source: Woman's World — https://womansworld.com/wellness/keltie-knight-gets-candid-on-how-prozac-killed-her-sex-drive
- Author: Lisa Maxbauer, Nealy Simms
- Published: 2026-10-01T22:00:38+00:00
- Read time: 1 min
- Topics: keltie knight, prozac, sex drive, hsdd, addyi, ladygang, perimenopause, ob-gyn, sprout pharmaceuticals, atrum health
## Keltie Knight's Experience
Keltie Knight, 44, says Prozac helped her feel emotionally stable but killed her sex drive.

> I just have been lowering my Prozac, and one of the main reasons I’ve wanted to is because I know that it has been killing my sex drive
## Antidepressants and Sex Drive
Antidepressants can affect sexual function, so changes in desire are worth discussing.

> I then went down and I started to feel not so bananas, and I was like, 'Oh, I guess I can’t have both.'
## The Conversation
Knight and cohosts created a livestream to normalize conversations women have in whispers.

> We really wanted to use this as an opportunity to have an actual conversation where we can talk about things we’re embarrassed to talk about
## The Gap in Care
There were 26 FDA-approved drugs for men’s sexual health but zero for women’s hypoactive sexual desire disorder.

> Then Cindy called bulls***
## Addyi's Role
Sprout Pharmaceuticals founder Cindy Eckert brought Addyi, an FDA-approved pill for HSDD, to market.

> What matters to women should matter to medicine
## Perimenopause and Desire
Dr. Davenport says bloodwork can be normal during perimenopause but desire shifts need attention.

> Your blood work is all over the place in perimenopause
## Finding Help
Knight recommends Addyi.com for private telehealth screening if doctors aren’t listening.

> If you don’t want to switch doctors because that seems like a very stressful thing, you have Addyi.com
## The Shift
Women speaking up about low desire is driving change in sexual health care.

> The ones who know if I don’t say it, it never changes
## What Happens Next
Knight’s new book, The F*ck Them Theory, releases November 24, focusing on radical honesty.

> That kind of vulnerability is becoming a personal mantra for Knight as she heads into what she calls her 'radical honesty era'
## Key takeaway

Keltie Knight, 44, says Prozac killed her sex drive but helped her emotionally, highlighting a common side effect of antidepressants.