# Lions beat Cardinals 45-21

> Detroit Lions dominate Arizona Cardinals with 45-21 victory.
- Title: Lions beat Cardinals 45-21 · Chicago Sun-Times | Shortify
- Summary: Detroit Lions dominate Arizona Cardinals with 45-21 victory. Detroit Lions defeated Arizona Cardinals 45-21 in NFL game on October 11, 2026.
- Keywords: lions, cardinals, nfl, jared goff, jameson williams, jahmyr gibbs, arizona cardinals, detroit lions, nfl game, football, news, local
- Source: Chicago Sun-Times — https://chicago.suntimes.com/nfl/2026/10/11/lions-offense-romps-in-a-45-21-win-over-the-cardinals
- Published: 2026-10-11T23:47:41.046+00:00
- Read time: 1 min
- Topics: lions, cardinals, nfl, jared goff, jameson williams, jahmyr gibbs, arizona cardinals, detroit lions, nfl game, football, news, local
## Lions' offense
Detroit scored three straight touchdowns and a field goal to take a 24-7 lead into halftime.
## Jared Goff's performance
Goff threw three touchdown passes, completing 19 of 30 passes for 279 yards.
## Jahmyr Gibbs' impact
Gibbs added 151 yards rushing and two more scores, scoring an NFL-record 58 touchdowns before his 25th birthday.
## Cardinals' struggles
Arizona has lost nine straight home games, a streak lasting more than a year.
## Harrison trade impact
Cardinals finalized trade to send Marvin Harrison Jr. to Houston Texans during first quarter.
## Lions' defense
Lions defense came into game giving up 31.8 points per game to rank No. 31 in NFL.
## Cardinals' quarterback
Brissett completed 29 of 47 passes for 292 yards, three touchdowns and one interception.
## Game result
Detroit Lions defeated Arizona Cardinals 45-21 on Sunday, October 11, 2026.
## Key takeaway

Detroit Lions defeated Arizona Cardinals 45-21 in NFL game on October 11, 2026.