# NFL Week 3 Betting Picks 2026

> SportsLine experts predict NFL Week 3 totals and spreads for Sunday's games
- Title: NFL Week 3 Betting Picks 2026 · CBS Sports | Shortify
- Summary: SportsLine experts predict NFL Week 3 totals and spreads for Sunday's games Chargers vs. Bills game likely to exceed 50.5 points
- Keywords: nfl, week 3, bills, chargers, seahawks, commanders, 49ers, cardinals, vikings, buccaneers, rams, broncos
- Source: CBS Sports — https://cbssports.com/nfl/news/nfl-picks-against-the-spread-week-3-2026-expert-ats-picks-predictions-player-props-this-weeks-games
- Published: 2026-09-27T16:21:38+00:00
- Read time: 1 min
- Topics: nfl, week 3, bills, chargers, seahawks, commanders, 49ers, cardinals, vikings, buccaneers, rams, broncos
## Bills vs Chargers
SportsLine predicts over 50.5 points in Bills-Chargers game

> So far, new chargers offensive coordinator mike mcdaniel isn't flexing much
## Browns vs Panthers
Browns favored by 2.5 points in Panthers-Browns matchup

> Bryce young has carved up two bad defenses but both were zone-heavy schemes
## Colts vs Texans
Colts favored by 1.5 points in Colts-Texans game

> Houston's offensive line is struggling with c.j. stroud facing more pressure
## Patriots vs Jaguars
Patriots favored by 3 points in Patriots-Jaguars game

> The patriots enjoyed a comfortable win against a steelers team that couldn't move the ball
## Giants vs Titans
Titans favored by 2.5 points in Giants-Titans game

> The titans averaged a healthy five point seven yards per play in their loss to philadelphia
## Seahawks vs Commanders
Seahawks favored by 7.5 points in Seahawks-Commanders game

> Drew lock has delivered strong numbers thus far with the washington defense having no answer for cee dee lamb
## Cardinals vs 49ers
Cardinals favored by 8.5 points in Cardinals-49ers game

> The forty nines started the season with a pair of blowouts while the cardinals crashed back to earth
## Vikings vs Buccaneers
Justin Jefferson over 68.5 receiving yards in Vikings-Buccaneers game

> Coming off a rain-soaked game in which the vikings hardly had the ball
## Rams vs Broncos
Rams favored by 2.5 points in Rams-Broncos game

> Aaron donald made his season debut and played thirty two snaps
## Eagles vs Bears
Eagles under 44.5 points in Eagles-Bears game

> The eagles have shown me nothing through two weeks on offense with three hundred and eighteen and three hundred and forty one yards
## Key takeaway

Chargers vs. Bills game likely to exceed 50.5 points