# NFL Week 5 Picks > SportsLine experts predict NFL Week 5 odds and prop bets for Sunday, Oct. 11. - Title: NFL Week 5 Picks · CBS Sports | Shortify - Summary: SportsLine experts predict NFL Week 5 odds and prop bets for Sunday, Oct. 11. SportsLine experts provide NFL Week 5 betting picks and prop bets for Sunday… - Keywords: nfl, week 5, sportsline, betting picks, prop bets, week 5 nfl, october 11, bears, packers, seahawks, 49ers, ravens - Source: CBS Sports — https://cbssports.com/nfl/news/nfl-picks-against-the-spread-week-5-2026-expert-ats-picks-predictions-prop-bets-for-sunday-oct-11 - Published: 2026-10-10T17:44:21+00:00 - Read time: 1 min - Topics: nfl, week 5, sportsline, betting picks, prop bets, week 5 nfl, october 11, bears, packers, seahawks, 49ers, ravens ## Week 5 NFL Schedule The Week 5 NFL schedule features top contests including Bears vs. Packers, 49ers vs. Seahawks, and Ravens vs. Falcons. ## Week 5 NFL Odds The Bears are 2.5-point favorites against the Packers, and the Rams are 3-point favorites against the Bills with an over/under of 54.5 points. ## Eagles vs. Jaguars Eagles Under 17.5 total team points with R.J. White citing injuries and travel challenges. > This spread has ballooned since it opened, with people fading a severely injured Eagles team ## Bears vs. Packers Bears (-2.5) with David Bearman highlighting their strong defense and time of possession. > It doesn't seem to matter who the qb is in chicago, as the bears still lead the nfl in total yards ## Texans vs. Titans Titans (+7.5) with Jeff Hochman noting their offensive line and weather conditions. > Tennessee's offensive line has allowed only six sacks, tying for the sixth fewest ## Raiders vs. Patriots Raiders (+3.5) with R.J. White analyzing their recent performance and rivalry dynamics. > The raiders saw a significant rise in quality of opponent in week four and largely rose to the challenge ## Giants vs. Commanders Cam Skattebo Under 77.5 total rushing + receiving yards with Alex Selesnick noting his struggles. > Cam Skattebo and the Giants' rushing attack have been largely ineffective this season ## Vikings vs. Saints Under 42.5 total points with R.J. White emphasizing the Vikings' defense. > The vikings are perhaps the biggest surprise through four weeks at 4 point zero ## Browns vs. Jets Quinshon Judkins Over 15.5 total carries with Larry Hartstein highlighting his performance. > The browns have handed the ball to a running back 67 times ## Colts vs. Steelers David Jones Under 219.5 total passing yards with R.J. White analyzing their strategy. > The colts went into their london game with a baffling game plan: establish the pass ## Broncos at Chargers Omarion Hampton Over 37.5 total rushing yards with Alex Selesnick noting his potential. > This looks like a nice buy low for omarion hampton, who has not lived up to expectations for a struggling chargers team ## Lions at Cardinals Michael Wilson Over 5.5 total receptions with Prop Bet Guy Doug highlighting his performance. > Michael wilson has notched 30 targets over the last two games with a wild 42 point six percent first read rate ## 49ers vs. Seahawks Seahawks (-2.5) with R.J. White noting their strong defense. > The forty nines are, by some accounts, the best team in the league, with a top three unit on both sides of the ball ## Ravens vs. Falcons Falcons (-2.5) with Mike Tierney highlighting their recent performance. > The falcons are back in primetime, right where they like it ## Bills vs. Rams Kyren Williams Over 89.5 total rushing + receiving yards with Alex Selesnick analyzing their strategy. > Kyren williams has been awesome for a struggling rams team and despite the team sputtering a bit ## Key takeaway SportsLine experts provide NFL Week 5 betting picks and prop bets for Sunday, Oct. 11 games.