# The 'chemo' supplement that could beat brain fog and fatigue

> Scientists find oxaloacetate helps breast cancer survivors with cognitive issues after chemo.
- Title: The 'chemo' supplement that could beat brain fog and fatigue
- Summary: Scientists find oxaloacetate helps breast cancer survivors with cognitive issues after chemo. Oxaloacetate supplement improves memory and concentration for…
- Keywords: oxaloacetate, breast cancer, chemo brain, cognitive symptoms, memory, concentration, fatigue, supplement, ucla, jco oncology advances, news, entertainment
- Source: Dailymail — https://dailymail.com/health/article-16223355/chemo-brain-supplement-beat-brain-fog-fatigue.html?ito=1490&ns_campaign=1490&ns_mchannel=rss
- Published: 2026-10-21T11:00:23+00:00
- Read time: 1 min
- Topics: oxaloacetate, breast cancer, chemo brain, cognitive symptoms, memory, concentration, fatigue, supplement, ucla, jco oncology advances, news, entertainment
## Oxaloacetate supplement claims
Users report lifting fatigue and brain fog within days of taking oxaloacetate.

> I feel like a brand-new person
## Oxaloacetate's role in body
Oxaloacetate is a compound produced naturally by the body that helps cells generate energy.
## UCLA study on breast cancer survivors
16 women taking oxaloacetate for eight weeks reported improved memory and concentration.
## Cognitive improvements
Scores on cognitive difficulty measures moved from impaired to normal range after eight weeks.
## Study limitations
The study was small and lacked a placebo group, so researchers cannot confirm oxaloacetate caused improvements.
## Digestive side effects
Two women stopped taking oxaloacetate due to nausea and bloating.
## Long Covid study
A separate study found oxaloacetate helped some long Covid patients with cognitive issues.
## ME/CFS benefits
Some ME/CFS patients reported reduced fatigue and improved cognitive function with oxaloacetate.
## Cost of supplement
At 1,000mg daily dose, oxaloacetate costs over $500 per month for a standard product.
## Long-term effects unknown
It's unclear if benefits last after stopping oxaloacetate or if longer courses are needed.
## Next steps
Researchers plan a larger placebo-controlled trial to confirm oxaloacetate's effects.
## Why it might work
Oxaloacetate could help restore normal cellular energy production or reduce neuroinflammation.
## Current recommendations
Experts caution oxaloacetate is not yet proven for brain fog and recommend more research.
## Oxaloacetate's potential
Early research suggests oxaloacetate could be a promising treatment for cognitive issues after cancer treatment.
## Key takeaway

Oxaloacetate supplement improves memory and concentration for breast cancer survivors with chemo brain.