# Week 2 NFL picks straight up and against the spread > Expert picks for every Week 2 matchup, plus survivor pool strategy and spread analysis. - Title: Week 2 NFL picks straight up and against the spread | Shortify - Summary: Expert picks for every Week 2 matchup, plus survivor pool strategy and spread analysis. The Eagles should dominate a weak Titans team, but watch out for… - Keywords: nfl, week 2, betting picks, spread picks, survivor pool, eagles, titans, jimmy kempski, phillyvoice, news, local, Week - Source: PhillyVoice — https://phillyvoice.com/week-2-nfl-straight-against-spread-and-survivor-pool-picks-eagles-titans - Published: 2026-09-17T12:37:28.775+00:00 - Read time: 4 min - Topics: nfl, week 2, betting picks, spread picks, survivor pool, eagles, titans, jimmy kempski, phillyvoice, news, local ## Eagles favored by 7 at Titans Philadelphia won Week 1 and faces a Titans team with a weak offensive line and no run defense after trading T'Vondre Sweat. The Eagles should cruise to 2-0. ## Bills favored over injury-hit Lions Buffalo is a 5.5-point favorite because Detroit will be missing starting offensive linemen Christian Mahogany and Blake Miller, plus cornerback D.J. Reed and both starting safeties. Too much to overcome. ## Packers overrated after Vikings loss Green Bay lost by 17 to Minnesota in Week 1, but the line is only 3.5 points against the Jets. If these teams had played Week 1, the spread would be much higher. The Packers feel overrated. ## Bears could be special after 59-point week Chicago put up 59 points on the Panthers in Week 1 and faces Minnesota as 4.5-point favorites. The Bears are on alert as a potentially special team this season. ## Patriots are the fraud team in AFC New England is favored by 5.5 over Pittsburgh despite looking like they'll regress after an unexpected Super Bowl run last season. The Steelers' defense is trustworthy enough for a tight game. ## Panthers defense vs Falcons offense Carolina is favored by 2.5 against Atlanta. Both teams had terrible Week 1 showings, but the Panthers' offense is more likely to score than the Falcons with Cooper Rush possibly starting. ## Buccaneers handle sloppy win over Browns Tampa Bay lost four fumbles in Week 1 but still only lost by 6 to Cincinnati. They'll beat the Browns by 8 and probably win the NFC South with 8 or 9 wins. ## Texans risky without Nico Collins Houston is favored by 2.5 over Cincinnati but Nico Collins injured his hamstring Wednesday. The Texans are helpless without him, similar to how the Eagles would be without DeVonta Smith. ## Ravens spread looks like overreaction Baltimore is favored by 9 over New Orleans after blowing out the Colts Week 1. The Saints looked impressive in their overtime loss to Detroit. This spread feels too high. ## Chargers knocked out survivor pools Week 1 Los Angeles lost at home to Arizona in Week 1, eliminating half the survivor pool entries. They get a gift schedule with home games against Arizona and Las Vegas to start. ## Broncos offense struggles like Eagles Denver couldn't sustain long drives in Week 1 like Philadelphia, except Jalen Hurts made big plays while Bo Nix didn't. The Jaguars look sharp and are favored against Denver. ## Cowboys-Commanders battle of flaws One of these NFC East teams will start 0-2. The Commanders looked better than expected Week 1 while the Cowboys' defense looked worse. Dallas wins but the Commanders get 4.5 points. ## Seahawks extend divisional dominance Seattle has won nine straight against Arizona and will make it 10 while laying 3.5 points. The Seahawks are the clear class of this division. ## 49ers huge favorites over Dolphins San Francisco is favored by 13.5 over Miami, one of the largest spreads of the season. The Dolphins might not win a game this year. > Maaannnn, a 13.5 spread already this season? The Dolphins might not win a game. ## Chiefs build around run game for Mahomes Andy Reid acquired Kenneth Walker and built Kansas City's offense around the run game while Patrick Mahomes recovers from ACL and LCL surgery. Smart adjustment for Week 2. ## Rams disappoint in Australia, Giants show competence Los Angeles was dominated by San Francisco in Week 1 after preseason hype about an undefeated season. The Giants showed competency we haven't seen in years. Take the 7.5 points. ## Against the spread picks for Week 2 Packers minus 3.5, Bears minus 4.5, Saints plus 9, Commanders plus 4.5, Seahawks minus 3.5, and Giants plus 7.5 are the best value plays this week. ## Survivor pool pick for Week 2 After getting knocked out Week 1 with the Chargers, the strategy shifts to avoiding overreactions to Week 1 results and targeting teams with favorable matchups. ## Key takeaway The Eagles should dominate a weak Titans team, but watch out for overreactions to Week 1 results when setting your bets.