# Week 4 NFL Odds Model Backs Giants and Seahawks

> Computer model predicts Giants and Seahawks cover spreads in Week 4 NFL games.
- Title: Week 4 NFL Odds Model Backs Giants and Seahawks · CBS Sports
- Summary: Computer model predicts Giants and Seahawks cover spreads in Week 4 NFL games. A computer model simulates NFL games 10,000 times and predicts Giants cover…
- Keywords: week 4, nfl, giants, seahawks, cardinals, chargers, computer model, betting picks, odds, spreads, sports, Week
- Source: CBS Sports — https://cbssports.com/betting/news/week-4-2026-nfl-odds-lines-spread-picks-predictions-best-bets
- Published: 2026-10-04T15:34:58+00:00
- Read time: 1 min
- Topics: week 4, nfl, giants, seahawks, cardinals, chargers, computer model, betting picks, odds, spreads, sports
## Week 4 NFL Odds Board
The Week 4 NFL odds board has 16 games before byes start Week 5.
## Colts vs. Commanders in London
Colts are favored by 4.5 points with Jayden Daniels (elbow) ruled out.
## Patriots vs. Bills
Patriots are favored by 7 points over Bills in Week 4 NFL spreads.
## Saints vs. Falcons
Saints are 2-point favorites over Falcons for the 20th anniversary of the Domecoming.
## Ravens vs. Titans
Ravens are 11.5-point favorites over winless Titans after Rio de Janeiro victory.
## Vikings vs. Dolphins
Vikings are 10-point favorites over 0-3 Miami despite Justin Jefferson (ankle) out.
## Giants Cover Prediction
Giants (+2.5, 44.5) cover against Cardinals with Arizona's recent losses.
## Seahawks Cover Prediction
Seahawks (-7, 42.5) cover against Chargers after 12-game win streak ended.
## Key takeaway

A computer model simulates NFL games 10,000 times and predicts Giants cover against Cardinals and Seahawks cover against Chargers in Week 4.