# Week 4 NFL Odds Model Picks

> Computer model backs Giants and Seahawks to cover spreads in Week 4 NFL games.
- Title: Week 4 NFL Odds Model Picks · CBS Sports | Shortify
- Summary: Computer model backs Giants and Seahawks to cover spreads in Week 4 NFL games. A computer model predicts the Giants and Seahawks will cover their spreads…
- Keywords: giants, seahawks, cardinals, chargers, nfl, week 4, odds, spreads, computer model, betting picks, sports, Week
- Source: CBS Sports — https://cbssports.com/betting/news/week-4-2026-nfl-odds-picks-predictions-bets
- Published: 2026-10-04T15:34:58+00:00
- Read time: 1 min
- Topics: giants, seahawks, cardinals, chargers, nfl, week 4, odds, spreads, computer model, betting picks, sports
## Week 4 NFL Odds Board
The Week 4 NFL odds board has 16 games with byes starting Week 5, including Colts vs. Commanders in London with Indy favored by 4.5 points.
## Giants and Cardinals Matchup
The Giants are 2.5-point favorites over the Cardinals with a total of 44.5 points, per the Week 4 NFL spreads.
## Seahawks and Chargers Matchup
The Seahawks are 7-point favorites over the Chargers with a total of 42.5 points, per the Week 4 NFL spreads.
## Model Performance
The computer model simulates every NFL game 10,000 times and has returned over $7,000 for $100 players since its inception.
## Week 4 NFL Picks
The model predicts the Giants cover against the Cardinals and the Seahawks cover against the Chargers in Week 4 NFL matchups.
## Week 4 NFL Betting Lines
Week 4 NFL betting lines include the Giants (-2.5, 44.5) vs. Cardinals, Seahawks (-7, 42.5) vs. Chargers, and other matchups with spreads and totals.
## Key takeaway

A computer model predicts the Giants and Seahawks will cover their spreads against the Cardinals and Chargers in Week 4 NFL matchups.