# Why Christina Applegate Was Misdiagnosed With MS

> Christina Applegate reveals she was misdiagnosed with multiple sclerosis after years of treatment.
- Title: Why Christina Applegate Was Misdiagnosed With MS | Shortify
- Summary: Christina Applegate reveals she was misdiagnosed with multiple sclerosis after years of treatment. Christina Applegate was misdiagnosed with multiple…
- Keywords: christina applegate, multiple sclerosis, misdiagnosis, neurologist, tirisham gyang, ms diagnosis, radiologic isolated syndrome, Christina, Applegate, Misdiagnosed, Rolling Stone
- Source: Rolling Stone — https://rollingstone.com/culture/culture-features/multiple-sclerosis-misdiagnosed-christina-applegate-1235645761
- Author: Elizabeth Yuko
- Published: 2026-10-20T22:06:59+00:00
- Read time: 1 min
- Topics: christina applegate, multiple sclerosis, misdiagnosis, neurologist, tirisham gyang, ms diagnosis, radiologic isolated syndrome
## Christina Applegate's Misdiagnosis
Christina Applegate revealed she was misdiagnosed with multiple sclerosis after five years of treatment.

> She came into my room and said, 'Congratulations, you don’t have MS'
## Seven-Month Break for Processing
Applegate took a seven-month break to process the diagnosis after receiving it from her doctor.
## Misdiagnosis Prevalence
A 2019 study found 20 percent of MS patients were misdiagnosed, with some studies showing up to 67 percent.
## Radiologic Isolated Syndrome
Some patients have no symptoms but show MS-like brain MRI results, called radiologic isolated syndrome.
## 2024 Diagnostic Criteria
Newer MS diagnostic criteria from 2024 include more tests to improve accuracy over older methods.
## Why Misdiagnoses Happen
Lack of a definitive MS biomarker and overlapping symptoms with other diseases cause frequent misdiagnoses.
## Treatment Risks
Patients without MS may take unnecessary immune-suppressing medications for MS.
## Financial Burden
MS treatment costs include medications, blood tests, and time off work, creating a significant financial burden.
## Key takeaway

Christina Applegate was misdiagnosed with multiple sclerosis, now working with doctors to find the real cause of her symptoms.