Misdiagnosis Confirmed

Christina Applegate shares she was misdiagnosed with multiple sclerosis five years ago.

“I’m sure people are saying, ‘Crybaby, you don’t have MS. You know, that’s a good thing,’””

Symptoms Started in 2021

Applegate first experienced numbness in her toes and legs in January 2021.

Initial Diagnosis

Her doctor initially said her symptoms weren’t showing signs of MS.

Revised Diagnosis

After additional testing, Applegate received an MS diagnosis with 40 brain lesions.

“Then finally came that day of the diagnosis when he said 'I’m so sorry,' and showed me the lesions on my brain, that were many, almost 40”

Treatment and Symptoms

Applegate underwent infusions for years but her symptoms worsened over time.

Misdiagnosis Revisited

Her doctor later said she didn’t have MS, but Applegate’s symptoms haven’t improved.

“I was not happy at all, everybody else was so happy.”

Physical Impact

Applegate uses wheelchairs to access doctor’s offices and can’t walk from her car.

Mental Health Strain

Applegate has experienced severe depression and lost her job due to her condition.

“I get really emotional because it stopped my life.”

Ongoing Investigation

Applegate and her medical team are starting an investigation into her symptoms.

“I’m back at square one that I don’t know what’s going on with me.”

Health Journey

Applegate has been hospitalized 30 times for MS-related symptoms.

“I've been in the hospital upwards of 30 times from throwing up and diarrhea and pain”

Family Impact

Applegate’s daughter Sadie Grace LeNoble has been affected by her condition.

“It was like losing the mom she had to this f, king thing.”

Humor as Coping

Applegate uses humor to cope with her condition and shares her struggles openly.

“I make these jokes because if I don't, I'll suffocate.”

Misdiagnosis Confirmed

Applegate was misdiagnosed with MS five years ago and now faces a new investigation.

“She came into my room and said, 'Congratulations, you don't have MS'”

Next Steps

Applegate and her medical team are starting an investigation into what could be causing her symptoms.

“I’m back at square one where I don't know what’s going on with me.”

Physical Therapy

Applegate continues physical therapy three times a week to manage her symptoms.

Long-Term Struggle

Applegate has been living with MS for over five years and her condition continues to worsen.

“I haven't gotten better, if anything, I've gotten worse.”