Vertex Q3 Earnings Target $500M Non-CF Revenue

Vertex's Nov 2 earnings reveal if new therapies hit $500M non-cystic fibrosis revenue target.

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Oct 26, 2026

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Vertex Q3 Earnings Target $500M Non-CF Revenue

Vertex's Nov 2 earnings reveal if new therapies hit $500M non-cystic fibrosis revenue target.

In brief

Vertex's Nov 2 earnings reveal if new therapies hit $500M non-cystic fibrosis revenue target. Vertex must hit $500 million in non-cystic fibrosis revenue by Nov 2 to prove it can scale beyond its core business. Originally reported by 24/7 Wall St..

Vertex Reports Q3 Earnings

Vertex Reports Q3 Earnings

Vertex Pharmaceuticals reports third-quarter results on Nov 2 with cystic fibrosis revenue still dominant.

Non-CF Revenue Target

VRTX price target

Vertex aims for $500 million in non-cystic fibrosis revenue from two newer therapies by Nov 2.

Q3 Revenue Growth

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Second-quarter revenue rose 12.4% to $3.33 billion, exceeding the $3.22 billion consensus.

CASGEVY and JOURNAVX Performance

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CASGEVY revenue rose 151% to $76.4 million, and JOURNAVX revenue quadrupled to $49.6 million.

Non-GAAP SG&A Spending

Non-GAAP SG&A rose 45% on pain and renal investments, with operating expenses at the high end of $5.65 billion to $5.75 billion.

Full-Year Revenue Guidance

Vertex raised full-year revenue guidance to $13.10 billion to $13.20 billion after closing the Crinetics acquisition.

Nov 30 FDA Action Date

Vertex faces Nov 30 FDA action for povetacicept in IgA kidney disease, with renal launch weeks away.

What matters most

Vertex must hit $500 million in non-cystic fibrosis revenue by Nov 2 to prove it can scale beyond its core business.

Read the original on 24/7 Wall St.

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